These results were presented today at a major medical meeting of psychiatrists. In this study, 42 percent of Cymbalta-treated patients met the definition of onset of efficacy compared to 35 percent of Lexapro-treated patients. Onset of efficacy was defined as at least a 20 percent decrease in Maier Subscale of the Hamilton Depression Rating Scale HAM-D17 at week two and sustained throughout eight weeks of acute treatment. While not indicative of faster onset of efficacy than Lexapro in patients with MDD, this study showed the onset of Cymbalta to be at least as fast as that of Lexapro.
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Cymbalta Sexual Side Effects In Females And Males
New Female Sex Drug May Treat Sexual Side Effects of Antidepressants | Center for Health Journalism
Because 1 in 6 women in the United States takes antidepressants and a substantial proportion of patients report some disturbance of sexual function while taking these medications, it is a near certainty that the practicing clinician will need to know how to assess and manage antidepressant-related female sexual dysfunction. Adverse sexual effects can be complex because there are several potentially overlapping etiologies, including sexual dysfunction associated with the underlying mood disorder. As such, careful assessment of sexual function at the premedication visit followed by monitoring at subsequent visits is critical. Treatment of adverse sexual effects can be pharmacological dose reduction, drug discontinuation or switching, augmentation, or using medications with lower adverse effect profiles , behavioral exercising before sexual activity, scheduling sexual activity, vibratory stimulation, psychotherapy , complementary and integrative acupuncture, nutraceuticals , or some combination of these modalities. Depression is a major risk factor for sexual dysfunction, and vice versa. A substantial proportion of patients will experience some disturbance of sexual function while taking antidepressants. Of note, although antidepressants are named for their effect on mood disorders, they are used in the clinical management of many other classes of psychological and physical problems, including but not limited to anxiety disorders, chronic pain, excessive weight, smoking, and menopausal hot flashes.
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Nearly one in four US women is on antidepressants. The drugs, like Prozac, Paxil and Zoloft, may be happy pills but they are not happy-in-the-bedroom pills. Both older and newer antidepressants cause severe sexual dysfunction like diminished libido and anorgasmia, the inability to achieve orgasm, even with adequate stimulation. Antidepressant sexual dysfunction is so common, it is used as a sales pitch by the drug manufacturers.